PhyNexus's PhyTip Columns
PhyNexus's PhyTip Columns

Protein A(MabSelect SuRe™/MabSelect SuRe™ LX) - PhyTip Columns, ProPlus / ProPlus LX Affinity resin

2022-06-03
조회수 651

제품 문의|주문, 데모 신청

The ProPlus (MabSelect SuRe™) and ProPlus LX (MabSelect SuRe™ LX) resin ligand is a recombinant Protein A derived ligand that demonstrates attributes of both Protein A and Protein G. ProPlus and ProPlus LX share a number of features including a modified Protein A ligand designed for alkali stability. Also, the modified Protein A is coupled to the resin matrix in an orientation that maximizes capacity. Choose ProPlus LX for high titer cultures to take advantage of high dynamic binding capacity. In certain cases, Protein G affinity resin will still demonstrate  superior selectivity over Protein A such as for certain isotypes and species of IgGs, including some mouse and rat IgGs.

ProPlus and ProPlus LX

  • Modified Protein A increases selectivity for Mouse IgGs
  • Optimal capacity due to ligand orientation
  • Capture, purify and enrich in as little as 15 minutes to obtain high concentrations of fully functional protein
  • Process small sample volumes in a reproducible, high throughput, automated format
  • Elution volumes as low as 10 μL, producing enrichment factors as high as 50 fold,  with concentrations of purified protein of up to 10 mg/mL
  • At least 10% higher capacity than Protein A resins
  • Broad range of selectivity, recognizing various isotypes and species, similar to Protein G
  • 3-5 fold greater recovery than Protein G

ProPlus LX

  • High dynamic binding capacity for high titer cultures


ProPlus / ProPlus LX columns with our proprietary Dual Flow Chromatography provide complete antibody binding and high final concentrations. PhyTip columns are compatible with most 8, 12, and 96-channel automation liquid handling robots including Agilent Technologies, Beckman Coulter, Dynamic Devices, HamiltonOpentrons, Perkin Elmer, and Tecan.

MabSelect SuRe and MabSelect SuRe LX are trademarks of GE Healthcare.


관련제품

PhyNexus MEA 2 | Fully Automated Protein Purification System