Molecular Diagnostics 3.0Powered by engineered molecular motors, our technology enables rapid, portable and scalable diagnostics
Innovative bioengineered motor proteins enable SHARP SHARP method is powered by a novel bioengineered PcrA-M6 helicase motor protein to split the DNA duplex at constant low temperature, while the conventional PCR requires a thermocycler to periodically heat the DNA above 95°C. SHARP performs equally well or better than the conventional PCR in terms of the sensitivity, specificity and speed. SHARP enables next-generation robust and portable point-of-care molecular tests for human disease detection and monitoring, including HIV, HCV, TB, Covid-19, Influenza etc. | 
We provide solutions for isothermal amplification
SHARP Diagnostics engineers enzymes for isothermal detection and amplification of nucleic acids and modified nucleic acids. We optimize isothermal assays for qualitative and quantitative molecular diagnostics. Our technology enables cost-effective single-step testing algorithms and it provides a clear path forward for future quantitative point-of-care and home HIV-1 and HCV tests.
Molecular Diagnostics 3.0
Powered by engineered molecular motors,
our technology enables rapid, portable and scalable diagnostics
Innovative bioengineered motor proteins enable SHARP
SHARP method is powered by a novel bioengineered PcrA-M6 helicase motor protein to split the DNA duplex at constant low temperature, while the conventional PCR requires a thermocycler to periodically heat the DNA above 95°C. SHARP performs equally well or better than the conventional PCR in terms of the sensitivity, specificity and speed. SHARP enables next-generation robust and portable point-of-care molecular tests for human disease detection and monitoring, including HIV, HCV, TB, Covid-19, Influenza etc.